蔬菜水果中植物化學物質防治肺癌作用及機制研究

   無論是在還是我國肺癌都是嚴重危害人類健康的惡性腫瘤。研究表明肺癌與環境因素以及生活方式密切相關流行病學發現多吃蔬菜水果可以預防肺癌。這些植物化學物質通過調節與抗腫瘤相關的通路從而抑制腫瘤細胞增殖、誘導腫瘤細胞凋亡降低肺癌發生的危險性。本文旨在對蔬菜水果中的植物化學物質在肺癌發生發展中的作用機制進行綜述為更好地預防和治療肺癌提供理論依據與方向。

Study on Effects and Mechanisms of Phytochemicals in Vegetables and Fruits ?in Preventing and Treating Lung Cancer

   Whether in the world or China, lung cancer is a malignant tumor which is harmful to human health. There were studies showed that lung cancer is tightly related to the environment factors and life style. The epidemiology study found that eating more fruits and vegetables can prevent lung cancer. Vegetables and fruits are rich in phytochemicals such as isothiocyanates, indoles, flavonoids and so on. These phytochemicals reduce the risk of lung cancer by modulating antitumor-related pathways such as inhibition of cell proliferation, induction of apoptosis, and the like. The aim of this review is to summarize the mechanisms of phytochemicals in vegetables and fruits in the pathogenesis and progression of lung cancer, so as to provide theoretical basis and direction for the prevention and treatment of lung cancer.

 

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